L-Cysteine hydrochloride monohydrate >

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제조사: Merck Millipore-AA

제품번호: 1.02735.0100

L-Cysteine hydrochloride monohydrate 요약정보 및 구매

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학술문의 전화번호	02-2140-5438
E-MAIL	ejan@younginlp.com
제품번호	1.02735.0100
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L-Cysteine hydrochloride monohydrate

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Product Information
CAS number	7048-04-6
EC number	200-157-7
Grade	Ph Eur,JP,USP
Hill Formula	C₃H?ClNO₂S * H₂O
Molar Mass	175.60 g/mol
HS Code	2930 90 16
Structure formula Image
Quality Level	MQ500

Physicochemical Information
Density	1.51 g/cm3
Melting Point	176 °C
pH value	0.8 - 1.2 (100 g/l, H₂O, 20 °C)
Vapor pressure	<0.1 hPa (20 °C)
Bulk density	780 kg/m3
Solubility	650 g/l

Safety Information according to GHS
RTECS	HA2285000
Storage class	10 - 13 Other liquids and solids
WGK	WGK 1 slightly hazardous to water
Disposal	3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.

Storage and Shipping Information
Storage	Store at +2°C to +30°C.

Specifications
Assay (alkalimetric, calculated on dried substance)	98.5 - 101.0 %
Identity (IR-spectrum)	passes test
Identity (specific rotation)	passes test
Identity (wet chemistry)	passes test
Appearance	white to almost white crystalline powder or colorless crystals
Appearance of solution (25 g/l, water)	clear and not more intense in color than reference solution BY?
Appearance of solution (100?g/l, water)	clear and colorless
pH (10?g/l, CO₂-free water)	1.3 - 2.3
Spec. rotation (α 20/D, 80?g/l, hydrochloric acid 250?g/l, calc. on dried substance)	+5.5 to +7.0
Spec. rotation (α 25/D, 80?g/l, hydrochloric acid 6?mol/l, calc. on dried substance)	+5.7 to +6.8
Spec. rotation (α 20/D, 80?g/l, hydrochloric acid 6?mol/l, calc. on dried substance)	+6.0 to +7.5
Sulfate (SO₄)	≤ 200 ppm
Heavy metals (as Pb)	≤ 10 ppm
Fe (Iron)	≤ 10 ppm
Related substances (TLC)	passes test
Related Compounds, total (TLC)	≤ 0.5 %
Ninhydrin-positive substances (LC) (impurity A (570 nm))	≤ 0.5 %
Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)	≤ 0.2 %
Ninhydrin-positive substances (LC) (ammonium (570 nm))	≤ 0.02 %
Ninhydrin-positive substances (LC) (total impurities)	≤ 1.0 %
Residual solvents (ICH Q3C)	excluded by manufacturing proces
Sulfated ash (600?°C)	≤ 0.1 %
Loss on drying (Vacuum < 2,0 kPa, P2O5, 20?h)	8.5 - 12.0 %
Bacterial endotoxins	≤ 6.0 I.U./g
Microbiological test (total aerobic microbial count (TAMC))	≤ 10²
Microbiological test (total yeast and mould count (TYMC))	≤ 10²
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph.?Eur., JP, USP.

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